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Dietary tocopherols inhibit cell proliferation, regulate expression of ER, PPAR, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia
This is known as bioavailabilitythe amount of a nutrient that reaches the bloodstream and becomes available for use by the cells
45 Liver cytochrome P450 (CYP450) enzymes regulate the biotransformation of targeted agents (e.g., imatinib, erlotinib), and polymorphisms in these enzymes can result in therapeutic failure or toxicity
Leslie WS, Ford I, Sattar N, Hollingsworth KG, Adamson A, Sniehotta FF, et al
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