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When exploring weight loss options, both Zepbound and Wegovy are noteworthy choices, each with distinct benefits that align with different health goals and lifestyles
Common Side Effects Both medications cause primarily gastrointestinal effects: Saxenda common side effects: Nausea (39%) Diarrhea (21%) Constipation (19%) Vomiting (16%) Injection site reactions (14%) Headache (14%) Dyspepsia (10%) Semaglutide common side effects: Nausea (44%) Diarrhea (30%) Vomiting (24%) Constipation (24%) Abdominal pain (20%) Headache (14%) Fatigue (11%) Side Effect Comparison Table Interpreting the Numbers Semaglutide appears to have higher rates of GI side effects in clinical trials
In the pancreas, GLP-1RAs are well known to promote insulin secretion
GIP increases adipose tissue expression and blood levels of MCP-1 in humans and links high energy diets to inflammation: a randomised trial
