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Dosing starts at 0.25 mg and then increases every four weeks, as needed and tolerated, up to 2.4 mg
In this sense, lower levels of Coprococcus, Faecalibacterium and Roseburia have been reported, while there seems to be an increase in bacteria populations that consume lactate, such as Megasphaera [86]
It's involved in cellular energy production and can be beneficial for individuals with fatigue or mitochondrial disorders
Most patients experience the greatest fatigue during weeks 14, with significant improvement by weeks 68
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