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Samarawickrama C, Wang JJ, Burlutsky G, Tan AG, Mitchell P
Multiple randomized controlled trials demonstrate that GLP-1 receptor agonists produce 15-22% average body weight loss over 68 weeks, with cardiovascular benefits including reduced blood pressure and improved metabolic markers
The availability of compounded GLP-1s without a prescription (illicit manufacturing and distribution) is a serious issue
These receptors are present on both neuronal cell bodies and axonal projections and are found in GABAergic and glutamatergic neurons depending on the region [71]
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