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Avoiding fatty, greasy, or heavily spiced foods during the initial titration period reduces gastrointestinal irritation

GLP-1 receptor agonists like semaglutide work best when dosed consistently, and the standard approach involves a single weekly injection that increases gradually over time

The choice between liraglutide and semaglutide for weight loss often depends on factors such as the patients medical history, their tolerance to the medication, and their preference for daily versus weekly administration

Alex Spencer (Metabolic Psychiatrist) Should Psychiatrists Prescribe GLP-1s? (drlewis.com), January 4, 2026