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Diarrhea often occurs due to reduced nutrient absorption , particularly fats, which creates an osmotic effect that draws water into the intestines
Bimagrumab, a monoclonal antibody targeting ActRIIA/IIB, inhibits myostatin and activins, promoting muscle hypertrophy and reducing fat mass
Even if GLP-1s have lower efficacy than an existing treatment (and there are indications that they may have higher efficacy), if they can reach many times more people, the overall public health impact would be massive
In some cases, the amount you need might exceed the capacity of your syringe, making it difficult, or even impossible, to measure and inject the right dose accurately
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