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FOXO4-DRI selectively induces apoptosis in senescent cells by disrupting the FOXO4-p53 interaction that keeps these damaged zombie cells alive, without harming healthy cells
Immunofluorescence tissues were mounted with ProLong Gold (Life Technologies, Cat# P36934), while H&E and immunohistochemistry tissues were mounted with Permount mounting media (Fisher Scientific, Cat# SP15500) and coverslipped for imaging
Seale et al., 2020
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