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GLP-1s are one of the most powerful tools in modern medicine offering benefits that may extend beyond weight loss to better metabolic health, cardiovascular function, and inflammation reduction
Understanding this metabolic interplay is important when considering newer therapeutic agents like tirzepatide for patients with coexisting autoimmune thyroid disease
Encouragingly, there are several ongoing and unreported preclinical, phase I/II trials investigating drugs utilising this dual mechanism of action [48]
SHBG, sex hormonebinding globulin
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