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Symptoms may include: Shortness of breath Red, flushed skin Headaches Rapid weight gain, polycythemia (increased red cell mass), hypokalemia, CHF, pulmonary edema, and vascular thrombosis are mostly observed in therapeutic contexts where vitamin B12 is administered aggressively or over extended periods

The products exist in a space where they are legal to sell as supplements but lack regulatory blessing for therapeutic use

Human safety data is limited, and long-term effects remain unknown

Both glycerol and fatty-acid release can be quantified in adipocytes or ex vivo adipose tissue, but measured values are affected by reuptake, re-esterification, substrate binding, sampling time, and nonlinear accumulation