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One study demonstrated that catechins, particularly epicatechin gallate, can activate GDF15 through the ATF3 transcription factor, independent of p53 [185]
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AMD is the leading cause of irreversible vision loss in adults over 50 years of age in the United States, affecting approximately 11 million Americans according to the National Eye Institute (NEI), with prevalence expected to increase as the population ages
These reviews provide opportunities to reinforce lifestyle modifications, adjust doses, and ensure patients remain suitable candidates for ongoing therapy
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