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Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites

Risk of bias assessment The results of evaluating the quality of the included studies are presented in online Supplementary Fig

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For optimal long-term results, dermatological experts recommend continuing maintenance treatment with copper peptide powder even after achieving desired improvements, as this prevents recurrence and provides ongoing protective benefits against environmental factors that trigger new pigmentation problems