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I 2 = 50%) were observed, with no changes in either HDL cholesterol (p = 0.61) or triglycerides (p = 0.09) (Supplementary Appendix)

The sensitivity has been stable or improving

Most studies have found a decrease in GLP-1 secretion in obese individuals [92], and some studies have found no difference in GLP-1 levels between obese and normal-weight controls [93]

From a formulation standpoint, this approach can create strong differentiation in markets where consumers are increasingly interested in clean beauty, herbal skincare, and naturally inspired formulations

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