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Description

Because its acetyl shield allows it to bypass the digestive tract and enter the cells intact, it provides an immediate infusion of active, reduced glutathione directly into the cytoplasm

The transcription factor NFE2L2 (Nrf2) positively regulates SLC7A11 expression, whereas tumor suppressors such as TP53, BAP1, and BECN1 downregulate SLC7A11 , increasing ferroptosis sensitivity (7880)