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This question comes up frequently, and the answer is nuanced
If you stop metformin because of side effects (GI distress, lactic acid concerns, kidney function), you can usually offset the A1C bump by maximizing semaglutide to 1.0 or 2.0 mg weekly
B6 plays a vital role in amino acid metabolism, neurotransmitter synthesis, and hemoglobin production
we investigated the effects of oxyntomodulin, exendin-4 and GLP-1 on neurite length, and sensitivity to capsaicin and ATP, in cultured DRG neurons
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