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The expression of genes involved in gluconeogenesis, glycogenolysis, lipid synthesis and transport, and catabolism were altered in untreated Hz animals and the expression of most of them was normalized by IGF-1 therapy
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Nevertheless, some models are more robust than others, and particular models may be of interest when testing compounds with specific mechanisms of action
"It's the reality of the world we live in now." Illustration: Emily Moskal / Stanford Medicine
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