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Epidemiological evidence shows that unhealthy dietary patterns, such as high-sugar, high-fat, and processed food intake, increase the risk of various cancers [32, 33]

All these factors may affect the sensitivity and specificity of serum B12 as a biomarker of B12 status and result in false-positive or false-negative classification of vitamin B12 deficiency

The injections given through drips are not painful but the injections given to muscles can lead to slight discomfort