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Treatment Options at Ro Weekly brand-name GLP-1 injections: Wegovy (semaglutide), Ozempic (semaglutide), Zepbound (tirzepatide) Daily injections: Saxenda (liraglutide) Compounded GLP-1 injections: semaglutide (availability limited

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Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

These CVOT findings are supported by a real-world study performed in over 3 million patients with T2DM from the United States, in which patients treated with SGLT2is did not have a higher risk of any or lower amputation compared with incretins or other glucose-lowering agents [77]