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Rat preparations of gastric ulceration, NSAID-induced gastrointestinal lesions, intestinal anastomosis, and inflammatory bowel injury have been the most frequently used systems, with the 2018 Zagreb review framing the molecule as a cytoprotective mediator across these preparations

2.2.5 Gut microbiota-based therapeutic interventions 2.2.5.1 Probiotics The results of human clinical trials (see Table 5) suggest that probiotics may be beneficial as a supportive therapy for PD