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B12 has been found to support healthy levels of nitric oxide, which when too high, can trigger headaches and migraines

This process known as first-pass metabolism or gastric first-pass metabolism acts as a partial filter, breaking down some alcohol before it enters systemic circulation

Overgrowth of bacteria: Some people develop vitamin B 12 deficiency as a result of conditions that slow the movement of food through the intestines (diabetes, scleroderma, strictures, diverticula), allowing intestinal bacteria to multiply and overgrow in the upper part of the small intestine

Methyl-free B vitamins that readily convert into methylated forms within your body