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The authors reported that the alleviation of NAFLD was related to the suppression of the Nod-like receptor protein amilypyrin domain containing 3 (NLRP3) inflammasome [13]
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A recent study has reported that some autophagy-modulating compounds which are reported to induce autophagy in mammalian systems, are effective in reducing Wolbachia levels and directly induce damage to nematode tissues in Brugia pahangi ( in vitro , compounds which induce autophagy only in the parasite would be less likely to cause off-target effects in humans
