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Vitamin B12 Deficiency in Dogs Without enough vitamin B12, many of a dogs enzymatic and metabolic processes cant proceed normally, which results in clinical signs like: Poor growth in young animals Anemia (low red blood cell counts) Neurologic dysfunction Importantly, these signs are also often seen with the very health problems that lead to vitamin B12 deficiency

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- People with significant liver disease (the 9-month monkey toxicology study showed dose-dependent periportal vacuolation in hepatocytes that the FDA flagged as a possible safety signal)