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Stool cultures from recurrent calcium oxalate stone formers show that they are only about half as likely to have colonies of this bacterium compared with non-stone formers, and those with O
When levels fall, mitochondrial efficiency declines and oxidative stress increases
however, its use is significantly limited by serious safety concerns, particularly teratogenicity and neurodevelopmental risks
Xeomin uses a purified form of the toxin without accessory proteins
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