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Treatment of bEnd.3 cells with SIS3 was able to partially restore the localization of claudin-5 to the cell membrane (Figure 6c)
Takahashi K, Murakami M, Hosaka K, Kikuchi H, Oshima Y, Kubohara Y
It is designed to provide a range of benefits, including brightening and evening out your skin tone, reducing the appearance of redness and blemishes, and providing anti-inflammatory properties that can help to reduce the appearance of fine lines and wrinkles.
This is paramount to maximize cardioprotection while minimizing potential off-target effects
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