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Certainty of evidence assessment The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) was used to determine the level of certainty of the evidence (Atkins et al
PMID 17074073
That "normal" concentration serum is no longer normal - it's hitting your dermis at dramatically higher levels than intended
Additionally, the drugs have been called anti-obesity medications (AOMs) by some researchers who criticize the drugs for the possibility of severe side effects, the lack of research into long-term use and the possibility of triggering eating disorders in some patients
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