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JAMA Network Open, 5(9), e2231982

The peptide exhibits multifaceted mechanisms, including tissue repair promotion via activation of growth hormone receptors and pathways like JAK2, which enhance collagen synthesis and fibroblast activity

If dietary measures are not sufficient, over-the-counter osmotic laxatives can provide relief without interfering with the peptide mechanism

Risk of lower extremity amputations in people with type 2 diabetes mellitus treated with sodium-glucose co-transporter-2 inhibitors in the USA: a retrospective cohort study

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