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The intermediates from de novo lipogenesis in the liver will disrupt mitochondrial function and produce ROS, and then cause endoplasmic reticulum (ER) stress, ultimately leading to inflammation, and the broken cells releasing cytokines will cause more cell death ( The excess free fatty acids (FFAs) and de novo lipogenesis would break the homeostasis of lipid metabolism
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One can use glutathione skin whitening supplements given by doctor or dermatologist
Your doctor will look at your test results and do more tests if needed to make a diagnosis and treatment plan
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