semaglutide shot locations How to Use Ozempic® Pen How to Inject Semaglutide |

Contrave also works on the mesolimbic areas of the brain and seems to have more benefits in those who describe cravings or food addiction, Nadolsky said

Notably, GLP-1R is abundantly expressed in various brain regions, including the hypothalamus, cortex, and hippocampus, as well as peripheral nervous tissues [10]

Given the similarities between the brain's and retina's vascular systems, these findings suggest that GLP-1R agonism could also protect the brain's microvasculature, preserving the integrity of the blood-brain barrier and improving cerebral blood flow

Studies show that GLP-1 weight loss drugs can reduce the risk of future health issueslike diabetes, high blood pressure, heart attacks, and strokesby up to 20% (Lancet, 2021)