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491 By regulating appetite, insulin secretion, and lipid metabolism, GLP-1RAs have potential benefits in the treatment of NAFLD, NASH, and T2DM
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The retatrutide results from the TRIUMPH-1 study are particularly noteworthy, where 45.3% of individuals on the 12 mg dose achieved a body weight reduction of 30% or more
Papers examine the degree and significance of lean mass loss during GLP-1 therapy, mechanisms underlying this effect, and potential mitigation strategies [13, 23]
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