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For example, in the SUSTAIN 5 clinical trial, patients with HbA1c levels of 8.0% or lower had their basal insulin doses reduced by 20% when starting semaglutide therapy to minimize the risk of low blood sugar
J Infect Chemother 25(8):571577 Hayashi A et al (2021) The butyrate-producing bacterium Clostridium butyricum suppresses Clostridioides difficile infection via neutrophil- and antimicrobial cytokine-dependent but GPR43/109a-independent mechanisms
Phase 2: Transition to Maintenance (Months 6-9) Once your weight has plateaued (typically around week 40-48 if you started escalation on schedule), it is time to find your maintenance dose
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