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Stimulant-based supplements: Products containing high-dose caffeine, bitter orange (synephrine), or ephedrine-like compounds may worsen anxiety, disrupt sleep, and increase cardiovascular risk concerns that are particularly relevant in people already managing chronic pain and fatigue

228 Studies involving animal models of sleep apnea and intermittent hypoxia have found that probiotics can improve some of the side effects of systemic inflammation in the heart and brain, as well as hypertension

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Autophagy and apoptosis go side by side, so studies investigating the crosstalk of such pathways concerning the role of miRNA can promote the current understanding of molecular mechanisms in PC