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Mutations at Hypothetical Binding Site 2 in Insulin and Insulin-Like Growth Factors 1 and 2 Result in Receptor-and Hormone-Specific Responses
Bias in meta-analysis detected by a simple, graphical test
Arginine at position 244 does not interfere with Glu235 and the substrate-deprotonation-process, as indicated by significantly lower K m values for Leu244Arg compared to Asn240Lys (Table 2)
Although the safety of metformin use in early pregnancy has been tentatively affirmed, additional data are required to definitively confirm its safety profile
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