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I notice that injecting my legs increases the chances of red marks 1 Like Beth April 15, 2026, 7:20pm #12 Im concerned with pain and too much copper but alas, Im also vain Is it worth it to buy powder for a diy serum, or is it no biggie once you are using tret

PMID 31959736

Bloom, S

This estimate is derived from comparative pharmacology and peptide absorption literature rather than from direct human studies: What This Means If you take 10 mg orally, approximately 3.8 mg reaches systemic circulation The remaining 6.2 mg is metabolized by stomach acid, proteases, and first-pass liver metabolism before reaching the bloodstream However, this systemic bioavailability may not directly reflect brain bioavailability (the amount reaching the central nervous system) Brain Penetration A critical distinction: systemic bioavailability (what enters the blood) differs from brain bioavailability (what crosses the blood-brain barrier and reaches neural tissue)