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What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data
However, niacinamide at physiological doses (like those in prenatal vitamins or moderate supplements) is not known to be harmful
It is strictly designated for laboratory research only and is not approved for human or animal administration
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