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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which means it mimics the effects of GLP-1, a naturally occurring hormone that regulates blood sugar levels and appetite
FAS is expressed in individuals with obesity and type 2 diabetes mellitus (T2DM) [34]
The recent direct-to-consumer/out-of-pocket strategies introduced by companies as lower cost options for their obesity medications, as well as more stringent payor/insurance coverage dynamics, could present some risk of even greater price erosion over the longer-term
