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[25] Cancer [edit] In response to a report of precancerous changes in the pancreases of rats and organ donors treated with the DPP-4 inhibitor sitagliptin, [26] [27] the US FDA and the European Medicines Agency each undertook independent reviews of all clinical and preclinical data related to the possible association of DPP-4 inhibitors with pancreatic cancer

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Treatment with CagriSema 2.4 mg OW SC resulted in an average 15.6% reduction in body weight, which was superior to the weight loss observed with cagrilintide 2.4 mg (8.1%) alone or semaglutide 2.4 mg (5.1%) alone [124]

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