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However, SURPASS-CVOT demonstrated non-inferiority to dulaglutide for MACE-3, providing relevant clinical signals for patients with type 2 diabetes and established cardiovascular disease[2][3]

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That is about double what we see with tirzepatide, nearly three times better than semaglutide and 4mmHg better than the CagriSema trials

However, it is important to note that some alternatives, like Contrave, carry a black box warning for suicidal thoughts and behaviors, which should be carefully considered when exploring options

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