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Menka Gupta, M.D., is a physician and functional medicine certified practitioner (IFMCP) in Singapore
Like GLP-1 agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, which block the degradation of GLP-1, also cause attenuation of the inflammatory responses
Key takeaways Food noise is the always-on mental chatter about food, distinct from physical hunger - researchers published its first formal clinical definition in 2025, and brain studies point to a specific appetite circuit that GLP-1 signals quiet down
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The injection is weekly and does not require a daily fasting window
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