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Importantly, while caloric restriction often leads to a loss of lean muscle mass, tesamorelin tends to preserve or slightly increase muscle tissue, a major advantage for patients seeking sustainable improvements in body composition

The most commonly reported side effects are mild and transient: injection site redness or minor bruising, transient fatigue in the first one to two weeks, and occasionally mild headache following the first few injections, a pattern sometimes attributed to the acute shift in cellular energy metabolism as AMPK pathways are upregulated [3]

Phentermine is one of the most common step therapy medications

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