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Possible explanations for this observation include beneficial HF effects of semaglutide that extend beyond weight loss, uncoupling of natriuretic peptide levels from the hemodynamic benefits as body weight is increasingly reduced, 10 as previously shown with other weight loss interventions, 11 , 14 or both
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Yes, the SUSTAIN-6 trial showed that Ozempic significantly reduced major adverse cardiovascular events, including non-fatal heart attack and stroke, in patients with type 2 diabetes and established cardiovascular disease or multiple risk factors
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