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For instance, it is reasonable to say a patient who is only able to tolerate a maintenance dose of 0.5mg may experience overdose severity symptoms if they were to take 3 to 4 weeks worth of doses (approximately 1.5mg to 2 mg) all at once, while other patients may not experience severe symptoms unless significantly higher amounts were administered

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2 and ESM Table 2)

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GLP-1, or glucagon-like peptide-1, is a hormone naturally produced in your gut that plays a crucial role in regulating appetite and metabolism

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