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Weight regain is common after stopping semaglutide without sustained lifestyle changes
There is also evidence for mechanisms involving a reduction of neuroinflammation, an increase in synaptic functioning, as well as the restoration of brain pathways of insulin signaling that may lead to improved memory formation and therefore a positive effect in Alzheimers disease and Parkinsons disease 34
This article examines the evidence, explores when Wegovy may or may not be suitable for people with a history of hypoglycaemia, and provides practical guidance on managing blood glucose levels during treatment
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