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Our experience shows that this effect is typically very mild and often diminishes with continued, consistent use as the body adapts
As the half-life of retatrutide is 6 days, once weekly administration was sufficient with as expected gastrointestinal disturbance being the most common side effect and occurring in 63% of those on retatrutide, 60% on dulaglutide, and 54% of the placebo cohort [63]
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