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They do not share the drawbacks of cyanocobalamin, but seem to have significant benefits
designed and applied highly active BirA to fruit flies and discovered 51 muscle-secreted proteins in the head and 269 fat-secreted proteins in the legs/muscles, including CG2145, a human homolog endoribonuclease (EndoU), which directly binds to muscles and promotes muscle activity [94]
doi: 10.1136/bmjopen-2020-046333 191
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