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Energy: 6
The resulting increase in intracellular NAD+ availability activates sirtuins particularly SIRT1, which regulates insulin sensitivity, gluconeogenesis, cholesterol synthesis, and fatty acid oxidation, and SIRT3, which governs mitochondrial antioxidant defences and energy metabolism
It differs from the unmodified 176-191 sequence by a single oxygen atom 1,815.1 versus 1,799.1 g/mol a difference that cannot be resolved by HPLC purity analysis alone
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