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For example, Aetna Better Health covers Zepbound for obstructive sleep apnea when used with a reduced-calorie diet and increased physical activity in patients who meet certain requirements, including a BMI of at least 30 and a moderate to severe sleep apnea severity

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Retatrutide binds three receptors: the GLP-1 receptor (regulates appetite, insulin secretion, and gastric emptying), the GIP receptor (influences insulin response and adipose handling), and the glucagon receptor (affects energy expenditure and hepatic lipid handling)

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