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Nutr Rev 2002;60:1424
Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action 5-Amino-1MQ works by blocking the NNMT enzyme , which is responsible for consuming nicotinamide and depleting NAD+ stores
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in diet-induced obese mice
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