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Although cytotoxicity was not specific to homocysteine, endothelial cell detachment is also observed with cysteine (Dudman et al, 1991), an increase in the hydrogen peroxide-sensitive cellular fluorescent probe, 2,7-dichloro-fluorescein, was observed in cultured endothelial cells exposed to homocysteine (Toborek and Hennig, 1996)
Pretreatment with alternate day modified fast will permit higher dose and frequency of cancer chemotherapy and better cure rates
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doi: 10.1038/s41467-019-12384-2 48 RichardLCHuiWenL
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