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The other principal sources of NADPH are from the glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase reactions in the pentose phosphate pathway and via the malic enzyme catalyzed reaction which is involved in the mobilization of mitochondrial acetyl-CoA to the cytosol

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has submitted its prospectus to the Hong Kong Stock Exchange , seeking initial public offering (IPO) listing to fund development of its advanced weight management therapy portfolio anchored by the GLP1 receptor agonist ecnoglutide (XW003) with broad obesity and metabolic indications , and supported by seven additional pipeline assets including oral GLP1 candidates and amylin analogs