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It affects approximately 20 million people worldwide and accounts for 5% of dementia cases 48
The canonical GST from Escherichia coli is a cytosolic -class enzyme whose three-dimensional structure has been solved at 2.1 resolution in complex with a glutathione analogue (PDB ID: 1A0F)
Without a strong myelin sheath, nerves are exposed and become damaged, which may even lead to nerve cell death
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