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There was no significant effect of GLP-1 RAs on mortality, although a nonsignificant favorable trend was observed in comparisons with placebo [100]
For example, overexpression of the transcription factor forkhead box o4 (FOXO4) in 3T3L1 cells inhibits CYP51A1 mRNA levels, leading to the intracellular accumulation of 24,25-dihydrolanosterol (DHL) and lanosterol
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